PTPhome.net - The Resource for Protein Tyrosine Phosphatases| HOME | RESOURCE | SEARCH | ABOUT | |
| PTPhome.net - The Resource for Protein Tyrosine Phosphatases |
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| HD-PTP, His-domain-containing protein tyrosine phosphatase |
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| Synonyms: | HD-PTP, HDPTP, PTP-TD14, KIAA1471, DKFZP564F0923 |
| Genomic Designation: | PTPN23 |
| Chromosomal Location: | 3p21.3 |
| ESTs | yes |
| Mouse | yes |
| Predicted MW or ORF: | 181.7 kDa (1636 aa). |
| Exp. Determined Mr: | 185 kDa |
| Post-translational Modif.: | none reported. |
| 3D Protein Structures: | none |
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| Tissue Expression: | |
| Reported Substrates: | |
| Function(s): | |
| Human Disease Assoc.: | |
| Comm. Avail. Reagents: | none known to us. |
| Reagents Avail. from us: | partial cDNA in pGEX, full-length cDNA in pEF3HA, polyclonal Ab. |
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| Domain Organization |
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| Amino Acid Sequence of Human ORF |
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References (in alphabetical order) Cao L, Zhang L, Ruiz-Lozano P, Yang Q, Chien KR, Graham RM, Zhou M. (1998). A novel putative protein-tyrosine phosphatase contains a BRO1-like domain and suppresses Ha-ras-mediated transformation. J. Biol. Chem. 273, 21077-21083. Qu X, Zhai Y, Wei H, Zhang C, Xing G, Lu C, Wang M and He F. (2001). Cloning, chromosomal assignment and tissue expression of a novel human protein tyrosine phosphatase (PTP-TD14) gene. I Chuan 23, 1-9. Toyooka S, Ouchida M, Jitsumori Y, Tsukuda K, Sakai A, Nakamura A, Shimizu N, Shimizu K. (2000). HD-PTP: A novel protein tyrosine phosphatase gene on human chromosome 3p21.3. Biochem. Biophys. Res. Commun. 278, 671-678. |
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| Content: Tomas Mustelin, Website: Lutz Tautz |
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